Annual report pursuant to Section 13 and 15(d)

Property and Equipment, Net (Details 2)

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Property and Equipment, Net (Details 2) - USD ($)
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Property, Plant and Equipment [Line Items]    
Depreciation expense $ 417,000 $ 528,000
Research and development [Member]    
Property, Plant and Equipment [Line Items]    
Depreciation expense 355,000 412,000
General and administrative [Member]    
Property, Plant and Equipment [Line Items]    
Depreciation expense $ 62,000 $ 116,000